Collagen & Aging

Collagen makes up 75% of skin dry weight and is the primary structural protein in joints, bones, tendons, and blood vessels. Production declines ~1% per year starting in the mid-20s, accelerating dramatically post-menopause (women lose ~30% of skin collagen in the first 5 years). By 60, most adults have lost 50%+ of their youthful collagen. GHK-Cu addresses this directly by activating collagen I, III, and IV synthesis, elastin production, and glycosaminoglycan (GAG) formation. Research at the Broad Institute showed GHK-Cu modulates ~4,000 human genes, essentially resetting gene expression to a more youthful pattern. Clinical studies show 70% response rate for measurable collagen increases.

The Midas Approach

The Midas Longevity Protocol doesn't address collagen & aging in isolation — it targets this pathway alongside 9 other aging mechanisms simultaneously. This multi-pathway approach reflects the scientific consensus that aging is not a single process but a network of interconnected pathways (Lopez-Otin et al., Cell 2023, "Hallmarks of Aging").

Learn more: 12 Hallmarks of Aging & How Midas Maps to Each