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NMN & NR vs Direct NAD+

Precursors vs direct administration · Bioavailability · Efficacy

NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are oral NAD+ precursors that must be converted through multi-step enzymatic pathways. Direct NAD+ bypasses these conversion steps entirely.

Comparison

FeatureNMN/NR (Oral)Direct NAD+ (Midas)
FormOral supplementLyophilized for reconstitution
Conversion Steps2-3 enzymatic steps requiredNone — direct
BioavailabilityVariable (oral absorption, first-pass metabolism)High (bypasses GI tract)
Dose CertaintyUnknown how much reaches cells as NAD+500mg NAD+ per vial
PuritySupplement-grade (variable)≥99% HPLC, Janoshik COA

The Midas Protocol uses direct NAD+ 500mg for maximum certainty and bioavailability.

Shop the Midas Longevity Protocol

12 compounds. 10 longevity pathways. 120 vials. ≥99% purity. Janoshik COA.

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Research Use Only. All products are for laboratory research only. Not for human consumption. No medical claims. Supplied by QSC (qscpeptide.com). ≥99% HPLC purity, Janoshik COA.